Biliary elimination of non-steroidal anti-inflammatory drugs in patients.

Non-steroidal anti-inflammatory drugs.

Hypersensitivity to non-steroidal anti-inflammatory drugs in pediatric patients

Results Medical records of 104 individuals with a history of hypersensitivity to drugs were analyzed. NSAIDs were the primarily suspected drug in 50% of the cases. The mean age was 10.9 years, with a predominance of males (57.7%). All patients had cutaneous manifestations and isolated angioedema was observed in the majority (53.8%); respiratory symptoms were reported in 44% of cases and gastroi...

Safety of non-steroidal anti-inflammatory drugs.

Non-steroidal anti-inflammatory drugs (NSAIDs) are widely used in medical practice for treating pain, inflammation and degenerative joint diseases (for instance, arthritis). The use of traditional NSAIDs (tNSAIDs), however, is associated with an increased risk of minor and serious gastrointestinal (GI) events. It is estimated that in the European Union thousands of gastrointestinal complication...

Isobolographic antinociception of non-steroidal anti-inflammatory drugs in rodent formalin orofacial pain

Diverse studies suggest that non-steroidal anti-inflammatory drugs (NSAIDs) induce antinociception through inhibition of cyclooxygenases. In this study was evaluated the effect of NSAIDs to induce antinociception either alone or in combination in the formalin orofacial test of rodent. Male mice were injected intraperitoneally with dexibuprofen, dexktoprofen, diclofenac meloxicam, metamizol, and...

Pnm-24: Pharmacologic Effect of Non-Steroidal Anti-Inflammatory Drugs in Reproductive System-(An Experimental Design

Background: Some patients that used Non-steroidal anti-inflammatory drug for a long time, as an analgesic, antipyretic or anti-inflammatory agent may be seen unusual effect of this drug on spermatogenesis and the level of blood testosterone hormone. The aim of this research is assess the effect of this drug on male-reproductive system functions Materials and Methods: This experimental research ...